Ultimate Windows Tweaker is a Tweak UI Utility for tweaking and optimizing Windows Vista, 32-bit & 64-bit. It can simply be downloaded and used as a portable application to customize your Windows Vista to meet your requirements. With judicious tweaking, it can make your system faster, more stable, and more secure with just a few mouse clicks. The tweaker detects whether you have IE 7 or IE 8 installed and accordingly offers you the relevant tweaks only.
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Works with Windows 7 also.