When it comes to managing mails, Outlook is the best companion a Windows user prefers. Outlook as a part of Microsoft Office, has lots of features as compared to other email programs. However, in some situations, if Outlook gets misconfigured, it wont start. Today, we’ll discuss one such issue, where we came around following error message, where Outlook simply refuses to start:
Cannot start Microsoft Outlook. Cannot open the Outlook window. The set of folders cannot be opened. The operation failed.
Upon receiving this strange error, you might try to restart your system and check if the issue fixes itself. You can also try to run Outlook in compatibility mode and see if this helps. For some users, it may resolve itself, while for others, a fix is needed to be applied. Here are the ways, which could help you to get rid of this issue:
Cannot start Microsoft Outlook
See if any of these help you.
1] Press
Windows Key + R and type following into the Run box, hit Enter key then:
Outlook.exe /resetnavpane
When you hit Enter key, Outlook will be started with resetting the profile settings. This should fix for you, else try the next fix.
2] Open Control Panel. Type
mail in the search box and hit Enter.

Click on the Mail icon which appears. In the Mail Setup – Outlook window, click
Show Profiles option.

In the Mail window, Add your new profile. Then choose
Always use this profile and select your newly added profile from drop down.
Click
Apply followed by
OK.

You can now restart your Windows PC and check if you can now open Outlook.
twc